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1

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms

David K Welsh, Diomedes E Logothetis, Markus Meister, Steven M Reppert

Journal:

Year:

1995

Language:

english

File:

PDF, 3.30 MB

english, 1995

2

Positive allosteric modulators of metabotropic glutamate 2 receptors in schizophrenia treatment

Ellaithy, Amr, Younkin, Jason, González-Maeso, Javier, Logothetis, Diomedes E.

Journal:

Trends in Neurosciences

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

3

PIP2 Activates KCNQ Channels, and Its Hydrolysis Underlies Receptor-Mediated Inhibition of M Currents

Hailin Zhang, Liviu C Craciun, Tooraj Mirshahi, Tibor Rohács, Coeli M.B Lopes, Taihao Jin, Diomedes E Logothetis

Journal:

Year:

2003

Language:

english

File:

PDF, 400 KB

english, 2003

4

Epilepsy-Related Slack Channel Mutants Lead to Channel Over-Activity by Two Different Mechanisms

Tang, Qiong-Yao, Zhang, Fei-Fei, Xu, Jie, Wang, Ran, Chen, Jian, Logothetis, Diomedes E., Zhang, Zhe

Journal:

Year:

2016

Language:

english

File:

PDF, 3.30 MB

english, 2016

5

Phosphoinositide Signaling Regulates the Surface Localization of the δ2 Ionotropic Glutamate Receptor

Petrou, Vasileios I., Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

6

Gating mechanism of a cloned potassium channel expressed in frog oocytes and mammalian cells

Koren, Gideon, Liman, Emily R., Logothetis, Diomedes E., Nadal-Ginard, Bernardo, Hess, Peter

Journal:

Year:

1990

Language:

english

File:

PDF, 1.62 MB

english, 1990

7

Coupling between the N- and C- Termini of Kir2.1 is Critical for Cholesterol Modulation

Rosenhouse-Dantsker, Avia, Logothetis, Diomedes E., Levitan, Irena

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 39 KB

english, 2013

8

The Lurcher Mutant of δ2 Ionotropic Glutamate Receptor is Regulated by Phosphoinositides

Petrou, Vasileios I., Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 37 KB

english, 2011

9

Stoichiometry of Kir channels with phosphatidylinositol bisphosphate

Jin, Taihao, Sui, Jin Liang, Rosenhouse-Dantsker, Avia, Chan, Kim, Jan, Lily, Logothetis, Diomedes E.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.11 MB

english, 2008

10

Regulation of Kv2.1 channel inactivation by phosphatidylinositol 4,5-bisphosphate

Delgado-Ramírez, Mayra, De Jesús-Pérez, José J., Aréchiga-Figueroa, Iván A., Arreola, Jorge, Adney, Scott K., Villalba-Galea, Carlos A., Logothetis, Diomedes E., Rodríguez-Menchaca, Aldo A.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 4.67 MB

english, 2018

11

Dynamic changes in phosphoinositide levels control ion channel activity

Diomedes E. Logothetis, Bernd Nilius

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 70 KB

english, 2007

12

G-protein coupling of a novel recombinant potassium channel

Marie-Noelle S. Langan, Kim W. Chan, Jin-Iiang Sui, Diomedes E. Logothetis

Journal:

Journal of the American College of Cardiology

Year:

1996

Language:

english

File:

PDF, 200 KB

english, 1996

13

Cholesterol Sensitivity of KIR2.1 Is Controlled by a Belt of Residues around the Cytosolic Pore

Rosenhouse-Dantsker, Avia, Logothetis, Diomedes E., Levitan, Irena

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

14

Potassium Channel Gating in the Absence of the Highly Conserved Glycine of the Inner Transmembrane Helix

Rosenhouse-Dantsker, Avia, Logothetis, Diomedes E.

Journal:

Year:

2007

Language:

english

File:

PDF, 784 KB

english, 2007

15

Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding

Diomedes E. Logothetis, Dmitry Lupyan, Avia Rosenhouse-Dantsker

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 615 KB

english, 2007

16

Cooperative Regulation of Slack Channel by Na+, Cl− and PIP2

Zhang, Zhe, Tang, Qiongyao, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 38 KB

english, 2012

17

Side-chain interactions in the regulatory domain of human glutamate dehydrogenase determine basal activity and regulation

Mastorodemos, Vasileios, Kanavouras, Konstantinos, Sundaram, Shobana, Providaki, Maria, Petraki, Zoe, Kokkinidis, Michael, Zaganas, Ioannis, Logothetis, Diomedes E., Plaitakis, Andreas

Journal:

Journal of Neurochemistry

Year:

2015

Language:

english

File:

PDF, 871 KB

english, 2015

18

Allosteric Effects of G-Protein Coupled Receptor Heteromerization: Relevance to Psychosis

Younkin, Jason, Baki, Lia, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

19

C-Type Inactivation in KV2.1 Channels

Villalba-Galea, Carlos A., Kawano, Takeharu, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2019

File:

PDF, 44 KB

2019

20

Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons

Plummer, Mark R., Logothetis, Diomedes E., Hess, Peter

Journal:

Year:

1989

Language:

english

File:

PDF, 1.19 MB

english, 1989

21

Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells

Baki, Lia, Fribourg, Miguel, Younkin, Jason, Eltit, Jose Miguel, Moreno, Jose L., Park, Gyu, Vysotskaya, Zhanna, Narahari, Adishesh, Sealfon, Stuart C., Gonzalez-Maeso, Javier, Logothetis, Diomedes E.

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2016

Language:

english

File:

PDF, 2.52 MB

english, 2016

22

Decoding the Signaling through Homomeric and Heteromeric Dopamine D2 and Cannabinioid CB1 Receptors

Xiang, Guoqing, Kawano, Takeharu, Baki, Lia, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 61 KB

english, 2016

23

A Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor Alters 5-HT2A Receptor Signaling in a Heteromeric Complex

Ellaithy, Amr, Younkin, Jason, Baki, Lia, Logothetis, Diomedes

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 42 KB

english, 2015

24

Ca 2+ -Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels

Tobelaim, William S., Dvir, Meidan, Lebel, Guy, Cui, Meng, Buki, Tal, Peretz, Asher, Marom, Milit, Haitin, Yoni, Logothetis, Diomedes E., Hirsch, Joel A., Attali, Bernard

Journal:

Year:

2017

Language:

english

File:

PDF, 1.40 MB

english, 2017

25

Protein Binding Pocket Optimization for Virtual High-Throughput Screening (vHTS) Drug Discovery

Gazgalis, Dimitris, Zaka, Mehreen, Abbasi, Bilal Haider, Logothetis, Diomedes E., Mezei, Mihaly, Cui, Meng

Journal:

Year:

2020

File:

PDF, 4.85 MB

2020

26

Requirement for an Activated G Protein α (Gα) Subunit for Gβγ Activation of a Purified Mammalian GIRk1 Channel Reconstituted in Planar Lipid Bilayers

Leal-Pinto, Edgar, Ha, Junghoon, Kawano, Takeharu, Zhang, Miao, Tang, Qiong-Yao, Gomez-Llorente, Yacob, Chavez, Jose, Ubarretxena, Iban, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 49 KB

english, 2014

27

Phosphoinositide Control of Membrane Protein Function: A Frontier Led by Studies on Ion Channels

Logothetis, Diomedes E., Petrou, Vasileios I., Zhang, Miao, Mahajan, Rahul, Meng, Xuan-Yu, Adney, Scott K., Cui, Meng, Baki, Lia

Journal:

Annual Review of Physiology

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

28

Pharmacological Implications of Adenosine 2A and Dopamine Type 2 Receptor Heteromerization

Yang, Yuchen, Hatcher-Solis, Candice N., Papakonstantinou, Maria P., Steiner, Albert A., Kawano, Takeharu, Plant, Leigh D., Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 47 KB

2020

29

CXCR4 modulates contractility in adult cardiac myocytes

Robert T. Pyo, Jinliang Sui, Ashwini Dhume, Julieta Palomeque, Burns C. Blaxall, George Diaz, James Tunstead, Diomedes E. Logothetis, Roger J. Hajjar, Alison D. Schecter

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2006

Language:

english

File:

PDF, 1.27 MB

english, 2006

30

SLO-2 isoforms with unique Ca 2+ - and voltage-dependence characteristics confer sensitivity to hypoxia in C. elegans

Zhang, Zhe, Tang, Qiong-Yao, Alaimo, Joseph T., Davies, Andrew G., Bettinger, Jill C., Logothetis, Diomedes E

Journal:

Year:

2013

Language:

english

File:

PDF, 5.55 MB

english, 2013

31

Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid PIP2

Ha, Junghoon, Xu, Yu, Kawano, Takeharu, Hendon, Tyler, Baki, Lia, Garai, Sumanta, Papapetropoulos, Andreas, Thakur, Ganesh, Plant, Leigh D., Logothetis, Diomedes E.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 14.51 MB

english, 2018

32

Molecular characteristics of phosphoinositide binding

Avia Rosenhouse-Dantsker, Diomedes E. Logothetis

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 381 KB

english, 2007

33

The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart

Logothetis, Diomedes E., Kurachi, Yoshihisa, Galper, Jonas, Neer, Eva J., Clapham, David E.

Journal:

Year:

1987

File:

PDF, 685 KB

1987

34

A Novel Site of Competitive PIP2 and Calmodulin Interaction to KCNQ1 C-Terminus Helix B is Crucial for IKs Channel Activity

Tobelaim, William S., Dvir, Meidan, Lebel, Guy, Cui, Meng, Buki, Tal, Peretz, Asher, Logothetis, Diomedes, Hirsch, Joel, Attali, Bernard

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 44 KB

english, 2016

35

Three pairs of Weak interactions precisely regulate the G-loop gate of Kir2.1 Channel

Li, Jun Wei, Xiao, Shao Ying, Xie, Xiao Xiao, Zhou, Hui, Pang, Chun Li, Li, Shan Shan, Zhang, Hai Lin, Logothetis, Diomedes E., Zhan, Yong, An, Hai Long

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2016

Language:

english

File:

PDF, 1.63 MB

english, 2016

36

Functional Crosstalk between mGluR2 and 5-HT2A Depends on their Expression Ratios

Baki, Lia, Eltit, Jose Miguel, Fribourg, Miguel, Younkin, Jason, Park, Gyu, Vysotskaya, Zhanna, Sealfon, Stuart C., Liapakis, George, Gonzalez-Maeso, Javier, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 37 KB

english, 2013

37

The ICl,swellinhibitor DCPIB blocks Kir channels that possess weak affinity for PIP2

Deng, Wu, Mahajan, Rahul, Baumgarten, Clive M., Logothetis, Diomedes E.

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

38

Competition of calcified calmodulin N lobe and PIP 2 to an LQT mutation site in Kv7.1 channel

Tobelaim, William Sam, Dvir, Meidan, Lebel, Guy, Cui, Meng, Buki, Tal, Peretz, Asher, Marom, Milit, Haitin, Yoni, Logothetis, Diomedes E., Hirsch, Joel Alan, Attali, Bernard

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.94 MB

english, 2017

39

Comparative Analysis of Cholesterol Sensitivity of Kir Channels: Role of the Cytoplasmic Domain

Rosenhouse-Dantsker, Avia, Leal-Pinto, Edgar, Logothetis, Diomedes E., Levitan, Irena

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 37 KB

english, 2010

40

Flexibility Between the Linker of the CD and G-Loops Determines the Gating Dynamics of Hte Kir2.1 Channel

An, Hailong, Li, Junwei, Zhan, Yong, Zhang, Hailin, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

41

Mutations in Nature Conferred a High Affinity Phosphatidylinositol 4,5-Bisphosphate-binding Site in Vertebrate Inwardly Rectifying Potassium Channels

Tang, Qiong-Yao, Larry, Trevor, Hendra, Kalen, Yamamoto, Erica, Bell, Jessica, Cui, Meng, Logothetis, Diomedes E., Boland, Linda M.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

42

The Molecular Mechanism of Opening the Helix Bundle Crossing (HBC) Gate of a Kir Channel

Meng, Xuan-Yu, Liu, Shengtang, Cui, Meng, Zhou, Ruhong, Logothetis, Diomedes E.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.85 MB

english, 2016

43

Alterations in Conserved Kir Channel-PIP2 Interactions Underlie Channelopathies

Coeli M.B. Lopes, Hailin Zhang, Tibor Rohacs, Taihao Jin, Jian Yang, Diomedes E. Logothetis

Journal:

Year:

2002

Language:

english

File:

PDF, 419 KB

english, 2002

44

Lick Rate and the Circadian Rhythm of Water Intake in the Rat: Effects of Deuterium Oxide

DIOMEDES E. LOGOTHETIS, ZIAD BOULOS, MICHAEL TERMAN

Journal:

Annals of the New York Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 183 KB

english, 1984

45

Regulation Of The Slo2.2 Channel By Na+ Ions And Phosphatidylinositol 4,5 Bisphosphate

Zhang, Zhe, Rosenhouse-Dantsker, Avia, Adney, Scott K., Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

46

Activation of the Atrial KAChChannel by the β γ Subunits of G Proteins or Intracellular Na+Ions Depends on the Presence of Phosphatidylinositol Phosphates

Jin Liang Sui, Jerome Petit-Jacques and Diomedes E. Logothetis

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.05 MB

english, 1998

47

PIP 2 Regulates the Ionic Current of P2X Receptors and P2X 7 Receptor-Mediated Cell Death

Zhao, Qi, Yang, Min, Ting, Adrian T., Logothetis, Diomedes E.

Journal:

Year:

2007

Language:

english

File:

PDF, 822 KB

english, 2007

48

Construction of G Alpha-16 Chimeras for Detection of GPCR Activation

Kawano, Takeharu, Baki, Apostolia, Xiang, Guoqing, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 40 KB

english, 2016

49

Positive Allosteric Modulators Induced Conformational Changes in the Metabotropic Glutamate Receptor 2 - In Silico Predictions and Experimental Tests

Xu, Yu, Ellaithy, Amr, Xiang, Guoqing, Danai, Manolakou, Agisilaos, Balatsoukas, Kawano, Takeharu, Cui, Meng, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 40 KB

english, 2016

50

Hydrogen Sulfide (H 2 S) Regulation of Kir (Inwardly Rectifying K+) Channels

Ha, Junghoon, Xu, Yu, Hendon, Tyler, Kawano, Takeharu, Garai, Sumanta, Thakur, Ganesh, Papapetropoulos, Andreas, Logothetis, Diomedes E.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 64 KB

english, 2017

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